海归学者发起的公益学术平台
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交流学术，偶尔风月
TwoPhDstudentshippositionsareopenforthefallsemesterinthelabofDr.ZhiyongCheng,DepartmentofFoodScienceandHumanNutritionatUniversityofFlorida.Thechosencandidatewillbesupportedbyfullscholarships.
Dr.Cheng’slabseekstounderstandthemolecularmechanismofmetabolicdiseases(obesityandtype2diabetes),withthegoalofdevelopingmechanism-basedstrategiesforearlydiagnoseandtreatmentofthediseases.Specifically,wearestudyingthecellularmechanismofadipocyteformationandexpansionduringobesitydevelopment,i.e.,howFoxO1andautophagyregulateadipogenesisandbeigingofwhiteadiposetissue(EijkelenboomandBurgering.NatureReviewsMolecularCellBiology;Altshuler-KeylinandKajimura.ScienceSignaling).Wecollaboratewithnano-medicineexpertstodevelopnano-devicestodeliverdrugstotreatobesityandmetabolicsyndrome.Anotherprojectongoinginthelabistostudytheepigeneticmechanismofdiabetesprogression,particularlyfocusingonDNAmethylation(Daveg?rdhCetal.MolecularMetabolism;ChengZ,etal.JournalofNutritionalBiochemistry).Thisisatranslationalresearchprogram,whereweusecellcultureforinvitromechanisticstudy,andrecruitobeseindividualstoexaminethepotentialofepigeneticmarkerstodiagnoseearly-stageprediabetesandassesstheeffectoflifestyleintervention.
UniversityofFloridaisoneofrenowneduniversitiesintheUS(#35NationalUniversities;#8TopPublicSchoolsaccordingtoUSNews).Dr.Chengis